MegaOmega (Microbiome Labs)
MegaOmega is the most comprehensive, full-spectrum fish oil scientifically formulated to support a healthy gut microbiome with a superior ratio of EPA, DHA and the “forgotten” DPA, as well as naturally-occurring metabolites called pro-resolving mediators (PRMs) shown to support a healthy immune and inflammatory response. MegaOmega is specifically formulated with higher EPA content than DHA content in order to support a healthy gut.
DPA, also known as the “forgotten fatty acid”, is receiving more attention in the omega-3 family due to its unique ability to increase EPA and DHA tissue status, but it also supports a healthy gut by reducing pro-inflammatory cytokines and macroscopic damage. Supplementation with DPA can also inhibit inflammatory cyclooxygenase (COX) pathways, resulting in healthier cells and tissues.
PRMs, or pro-resolving mediators, are omega-3 derivatives that are responsible for terminating an inflammatory response and repairing damaged tissue through a process known as remediation. PRMs fall into four families: lipoxins, resolvins, protectins, and maresins. They resolve everyday inflammation by sequestering proinflammatory cytokines, clearing neutrophils and inflammatory debris, and increasing lymphatic removal of phagocytes following an inflammatory response.
While the human body is able to convert omega-3’s to PRMs, the process is time-consuming and requires multiple steps to complete. Furthermore, it can be inhibited due to stress, disease, genetics, diet and lifestyle factors. Supplementation provides the body with an abundance of PRMs, so that remediation and tissue restoration can proceed quickly and without limitation.